Postdoctoral Fellow | |
| Job ID | FF-4D-B9-E7-4A-CC |
| Company | Ontario Institute For Cancer Research |
| Location | Toronto |
| Province | Ontario |
| Date Posted | 2023-11-08 |
| Posted Until | 2024-05-06 |
| Job Type | Full-time |
| Job Category | Miscellaneous |
| Description | |
| The Ontario Institute for Cancer Research (OICR) is seeking a Postdoctoral Fellow with expertise in cancer biology for its Drug Discovery Program. The successful candidate will have drug discovery experience and knowledge of oncology target validation, assay development, and drug screening. This position is temporary, full-time for two years. The OICR Drug Discovery Program is one of the largest programs of its kind in Canada. Our mission is to help efficiently translate discoveries made in Ontario's labs into novel oncology therapies. The team is comprised of more than 25 researchers whose collective expertise spans the entire drug discovery process from target identification and validation to clinical candidate selection. The group has extensive drug discovery experience within pharma and biotech environments and combines the disciplines of biology, ADME/PK, analytical, medicinal, and computational chemistry expertise along with state-of-the-art infrastructure necessary to successfully conduct drug discovery projects. OICR is Ontario's cancer research institute. We bring together people from across the province and around the world to improve the lives of everyone affected by cancer. We take on the biggest challenges in cancer research and deliver real-world solutions to find cancer earlier and treat it more effectively. We are committed to helping people living with cancer, as well as future generations, live longer and healthier lives. Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Colleges and Universities. Position responsibilities include: Develop and conduct relevant cell-based assays to screen small molecule drug candidates and support SAR to move projects from screening, through hit assessment, and into lead generation and optimization. Validate oncology drug discovery targets using established genetic techniques (siRNA, shRNA, CRISPR) with associated rescue experiments. Maintain meticulous records of experimental procedures and data. Liaise effectively with multi-disciplinary team members (computational chemistry, medicinal chemistry, and ADME groups) within the Drug Discovery Program, with other OICR Research Programs, and with academic and industry collaborators. Participate in team meetings, both internal and external. Assist in day-to-day lab management, such as reagent inventories, reagent ordering, instrument maintenance, and generation/updating of SOPs. Work effectively under pressure and tight timelines. Communicate effectively with internal and external collaborators. Adhere to all OICR safety guidelines and policies, strongly advocates safety to others. Qualifications: PhD degree, obtained within the last four (4) years, in Biochemistry or Cell Biology with experience in drug discovery. Experience in the development / execution of small molecule cell based screens. Experience in the development of cell-based target engagement and functional assays to support medicinal chemistry efforts. Experience in the validation of novel anti-cancer targets using genetic techniques. Familiarity with the drug discovery processes and timelines in general. Knowledge of cancer biology and related signal transduction pathways. Great team player with excellent interpersonal and communication skills. Highly motivated self-starter who enjoys an element of ambiguity and is willing to adapt to a changing environment. For more information about OICR, please visit the website at www.oicr.on.ca. To learn more about working at OICR, visit our career page. CLOSING DATE: Until Filled | |
| Languages | English |
| How To Apply | Click "Apply Now" If you are interested in being considered for this position, please go to the job link above and click on "Apply" at the bottom of the page. OICR is committed to fostering a climate of equity, diversity, inclusion, and accessibility. This commitment is central to, and mutually supportive of, our research excellence mandate. We welcome and respect the diversity of all members of our community and we support an inclusive culture for all. We welcome all applicants, and encourage applications from racialized persons, Indigenous Peoples, women, persons with disabilities, LGBTQ2S persons, and others who may contribute to furthering a diversity of ideas within our community. OICR is committed to fair assessment of a candidate's abilities, and consideration for diversity of thought, method, and experience. Providing an accessible workplace and recruitment process is important to us, as described in our Accessibility Plan (https://oicr.on.ca/accessibility/). Should you require accommodation during any stage in the recruitment process, please complete the form at the bottom of page https://oicr.on.ca/careers/. Information received related to accommodation will be handled confidentially. The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted. Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .pdf or .doc file. |
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